Because so many people have neurological disorders, research to prevent, treat or cure them is essential.
Here at the OHSU Brain Institute, we bring doctors, laboratory scientists, and neurological experts together to develop advanced treatments and prevention strategies.
We’ve compiled a list of just a few of the more recent research innovations coming from our labs:
- Javits Award – Dr. Mary Heinricher receives $2.3 million Jacob Javits Neuroscience Investigator Award for her research into chronic pain: Portland Business Journal, and OHSU School of Medicine
- A study led by Dr. Susan Ingram suggests an avenue for developing treatments for chronic pain that harness the medicinal properties of cannabis while minimizing the threat of addiction: OPB-Radio story picked up by KUOW-Radio, The Lund Report and the Klamath Falls Herald & News; UPI.
- An OHSU study in rodents that found sensitivity to pain can be spread by smell is among STAT’s (Boston Globe’s) favorite “Huh?” moments of 2016.
- A team of scientists led by Marc Freeman, Ph.D., director of the Vollum Institute, documented a newly understood pathway for transmitting signals within the brain. The research findings, published in the journal Nature, demonstrate that glial cells not only support but actively participate in processing information in the brain. The research provides the first in vivo demonstration of astrocyte calcium signaling as essential for behaviors such as olfactory or startle responses.
- Research findings published Nov. 28 in JAMA Neurology by Jeffrey Iliff, Ph.D., assistant professor in the Department of Anesthesiology and Perioperative Medicine, School of Medicine, suggest the aquaporin-4 protein may be a new target for potentially preventing and treating Alzheimer’s disease.
- OHSU’s deaf scientists lead charge in hearing research. (The Oregonian, Nov. 25.)
- OHSU researchers brought in over $389 million in fiscal year 2016.
- The National Institute’s of Health is OHSU’s most significant source of funding, providing over $230 million last year.
- There are 1,250 principal investigators at OHSU, working on 2,240 research projects.
- Researchers from the Vollum Institute have identified the repressor/ corepressor complex responsible for controlling the ratio of neurons and glia cells in the embryonic brains of mice.
- Jacob Raber, Ph.D., and a team of OHSU scientists published findings in the journal BMC Genomics that suggest long-term exposure to cosmic radiation, particularly to Iron-56 ions, may cause symptoms ranging from memory problems to impaired judgment in astronauts. The research, conducted on mice, suggests effects that are both short and long term.
- Lack of deep sleep may set the stage for Alzheimer’s
Dr. Jeffrey Iliff and Dr. Bill Rooney discuss their research that recently received funding from the Paul G. Allen Foundation.
- Mysterious antidepressant target reveals its shape (Nature, April 6)
- Determining why some drink to intoxication; OHSU scientists conducting research to identify problem drinkers before they become addicted (The Columbian, March 28)
- Carol Borges-Merjane and Larry Trussell, Ph.D., authored the cover story of the March 4 issue of Neuron in an article titled “ON and OFF unipolar brush cells transform multisensory inputs to the auditory system.”
- Michael Cohen, Ph.D., was named to the 2015 class of Pew Scholars. His research concerns how ADP-ribosyltransferases affect learning, memory, and other brain functions.
- OHSU Researchers make breakthrough discovery in diabetes-related blindness
Henrique von Gersdorff, Ph.D. is interviewed by Portland Business Journal.