How our brains wash away the gunk during sleep

You wake on Saturday morning, drag your body out of bed and survey your home. You had entertained houseguests the night before, and it shows. Friends and family had filled your home, loud voices and...

‘Neuroprotection’: an elusive goal in fighting brain diseases

About 15 years ago, I wrote an article about treating Alzheimer’s disease that divided treatments into two categories: “symptomatic” and “neuroprotectant.” There were real options in the...

The continuing search for the answer to Alzheimer’s disease

Alois Alzheimer, a German physician in 1906, was studying a woman who came to his clinic complaining about memory loss, language problems, and behavioral changes. She ultimately died of...

False hopes and real risks with Alzheimer’s ‘treatments’

“What do I have to lose?” I hear this question regularly from patients who want to try the latest “breakthrough” in Alzheimer’s research featured on television or YouTube.  These are...

Is ‘tau’ the new front line in the Alzheimer’s fight?

Patients and their family members have been bringing me clippings from that famous medical journal, "The Wall Street Journal," asking me if it's true that Alzheimer's research is now focused on...

New test that predicts Alzheimer’s?

What if we could predict who would one day go on to develop Alzheimer’s disease? There is no definitive test for Alzheimer's disease. Neurologists and others who specialize in treating dementia...

How do we measure success in treating Alzheimer’s?

My first couple of blog posts were focused on directions in research on Alzheimer’s disease. So this time I’d like to turn to the routine clinical care of patients with Alzheimer’s disease and...

The challenge of testing new Alzheimer’s drugs

We Alzheimer’s disease specialists get a lot of free advice. One of the most common recommendations is that we should work on a way to prevent Alzheimer’s in healthy people rather than try to fix...