Finding new treatment targets for aggressive prostate cancer, lymphoma and leukemia. Visualizing how breast tumors grow resistant to drug therapy. Using mobile phone sensors to track symptoms in patients with pancreatic cancer. These are some of the new pilot projects funded by the OHSU Knight Cancer Institute.
The $50,000 grants help early career and senior investigators generate preliminary data to pursue more expansive funding from external, peer-reviewed sources such as the National Institutes of Health. The awards are made possible by support from philanthropic donors and the Knight Cancer Institute’s NCI Cancer Center Support Grant.
Anupriya Agarwal, Ph.D., Shannon McWeeney, Ph.D., Andrew Adey Ph.D.
Microenvironment-driven inflammatory signals: A role in clonal evolution of pre-leukemia cells in AML
Albert and Elaine Borchard Foundation
Joshi Alumkal, M.D., Laura Heiser, Ph.D., and Xiangshu Xiao, Ph.D.
Targeting CREB1 in Enzalutamide-Resistant, Lethal Prostate Cancer
Noel and Carolyn Lesley
Kimberly Beatty, Ph.D., and Jim Korkola, Ph.D.
Imaging drug-resistance mechanisms in HER2-positive breast cancer
The Hillcrest Committee
Lulu Cambronne, Ph.D.
How cancer metabolism banks on mitochondrial NAD+
The Hillcrest Committee
Alexey Danilov, M.D., Ph.D., and Peter Hurlin, Ph.D.
Targeting c-Myc by selective inhibition of cyclin-dependent kinase-9 (CDK9) in diffuse large B-cell lymphoma
Albert and Elaine Borchard Foundation
Jessica Leonard, M.D.
Identifying novel signaling pathways in Adult ALL
Albert and Elaine Borchard Foundation
Daniel Marks, M.D., Ph.D., and Aaron Grossberg, M.D., Ph.D.
Mobile device-collected actigraphy as a tool for early detection and symptom monitoring in patients with pancreatic cancer
Kemmerer Foundation
Amanda McCullough, Ph.D., and R. Stephen Lloyd, Ph.D.
DNA Base Excision Repair as a New Target for the Treatment of Acute Myeloid Leukemia
Noel and Carolyn Lesley
Philip Streeter, Ph.D.
Monitoring Pancreatic Cancer Recurrence by High Resolution Flow Cytometry
The Hillcrest Committee
