New clues to what turns prostate cancers deadly

Only a fraction of prostate cancers become life threatening, but it’s impossible to predict which ones. In a surprising new study, researchers found that two signaling proteins used by nerve cells...

Jamming fat metabolism stops blood cancer cells

Targeted cancer therapies work by blocking specific, cancer-driving mutations. But in a new laboratory study, researchers show that cancers driven by several different mutations can all be stopped by...

‘Scissor’ opens view to single cells of cancer, other diseases

Cancerous tumors are composed of cells that may look the same but are in fact incredibly diverse. Mutations and changes in gene activity give rise to competing sub-populations of tumor cells with...

Targeting uniquely dangerous postpartum breast cancers

Breast cancers that emerge within five to ten years of pregnancy are more likely to become life-threatening. A new study finds that these postpartum breast tumors represent a unique subtype of cancer...

Overcoming drug resistance to stop a deadly blood cancer

Cancer researchers have discovered a potential way to make targeted therapy drugs more effective and longer lasting for people with acute myeloid leukemia, or AML. The scientists showed how it is...

Discovery sheds light on early-onset colorectal cancer

The rapid rise of colorectal cancer in younger people remains perplexing, but a new study fills in a missing piece of the puzzle. Researchers found that three genes involved in immunity and...

Innovation expands view into workings of single cells

Researchers have devised a way to multiply by more than ten-fold the accessible details of gene activity in individual cells. It’s a big leap in the effort to understand cancer development, brain...

Engineering models of early cancer: Q&A with Carolyn Schutt Ibsen

Carolyn Schutt Ibsen, Ph.D., develops biomaterials that can be controlled remotely and noninvasively using ultrasound. She and her team at OHSU are using these “energy-responsive” materials to...

Perturbed tumors reveal their secrets

A trove of freely accessible cancer data helps researchers find new combination treatments. Targeted cancer therapies work by blocking a specific cancer-driving signal, thus limiting harm to healthy...

Interrogating cancer, one cell at a time: Q&A with Hisham Mohammed

Hisham Mohammed, Ph.D., helped create a way to peer into individual cells and take multiple measures of gene activity and gene regulation at the same time. He’s leading the first research to apply...