Overcoming drug resistance to stop a deadly blood cancer

Cancer researchers have discovered a potential way to make targeted therapy drugs more effective and longer lasting for people with acute myeloid leukemia, or AML. The scientists showed how it is...

Discovery sheds light on early-onset colorectal cancer

The rapid rise of colorectal cancer in younger people remains perplexing, but a new study fills in a missing piece of the puzzle. Researchers found that three genes involved in immunity and...

Innovation expands view into workings of single cells

Researchers have devised a way to multiply by more than ten-fold the accessible details of gene activity in individual cells. It’s a big leap in the effort to understand cancer development, brain...

Engineering models of early cancer: Q&A with Carolyn Schutt Ibsen

Carolyn Schutt Ibsen, Ph.D., develops biomaterials that can be controlled remotely and noninvasively using ultrasound. She and her team at OHSU are using these “energy-responsive” materials to...

Perturbed tumors reveal their secrets

A trove of freely accessible cancer data helps researchers find new combination treatments. Targeted cancer therapies work by blocking a specific cancer-driving signal, thus limiting harm to healthy...

Interrogating cancer, one cell at a time: Q&A with Hisham Mohammed

Hisham Mohammed, Ph.D., helped create a way to peer into individual cells and take multiple measures of gene activity and gene regulation at the same time. He’s leading the first research to apply...

Stopping the secretive cells that revive deadly tumors

Cancers are notorious for their ability to rebound uncontrollably after a first round of successful treatment. In a new study, researchers at OHSU have uncovered how a fraction of a tumor’s cells...

How scientists are mapping the cancer ecosystem to find cures

Cancer is more than just tumor cells driven by gene mutations. Cancer is like an ecosystem filled with evolving populations of tumor cells that interact with and enlist support from neighboring...