Knight Cancer signal achievements of 2022
People at the Knight Cancer Institute accomplished a lot in 2022. Through innovative, collaborative research and education, the institute delivers cancer prevention, detection, and care — one...
Category: cancer biology
Taking a systems approach to beating cancer
Diversity and adaptability make cancer hard to beat. To survive, tumors find many ways to cooperate with immune and other host cells, and tumors avidly split into sub-populations of cancer cells with...
OHSU scientists represent at AACR
A Knight Cancer Institute scientist took the reins as president of the American Association for Cancer Research. Another joined the prestigious ranks of AACR fellows. And a...
Sex hormones limit cancer immunotherapy success
Scientists have discovered how the sex hormone androgen, most commonly testosterone in men, can limit the body’s response to cancer immunotherapy, a finding that may help make those therapies more...
Study reveals inherited risk of leukemia
Inherited mutations that increase the risk of developing a dangerous blood cancer are more common than previously appreciated, a new study reveals. Researchers analyzed acute myeloid leukemia...
Detecting tumor responses before they become deadly
Targeted cancer therapies can be stunningly effective at blocking specific, cancer-driving signals. But all too often, tumors develop resistance by switching to alternative signaling pathways to...
New clues to what turns prostate cancers deadly
Only a fraction of prostate cancers become life threatening, but it’s impossible to predict which ones. In a surprising new study, researchers found that two signaling proteins used by nerve cells...
Jamming fat metabolism stops blood cancer cells
Targeted cancer therapies work by blocking specific, cancer-driving mutations. But in a new laboratory study, researchers show that cancers driven by several different mutations can all be stopped by...
‘Scissor’ opens view to single cells of cancer, other diseases
Cancerous tumors are composed of cells that may look the same but are in fact incredibly diverse. Mutations and changes in gene activity give rise to competing sub-populations of tumor cells with...
Targeting uniquely dangerous postpartum breast cancers
Breast cancers that emerge within five to ten years of pregnancy are more likely to become life-threatening. A new study finds that these postpartum breast tumors represent a unique subtype of cancer...
Overcoming drug resistance to stop a deadly blood cancer
Cancer researchers have discovered a potential way to make targeted therapy drugs more effective and longer lasting for people with acute myeloid leukemia, or AML. The scientists showed how it is...