Studies reveal new ways to fight a deadly leukemia

One study shows how it may be possible to stop acute myeloid leukemia by targeting a hidden population of cells that support the cancer. Another reveals how AML evolves to evade anti-cancer drugs,...

New path to stop drug-resistant breast cancer

Even when anti-cancer drugs appear to eliminate tumors, a resistant few malignant cells can survive and allow cancers to resume a fatal onslaught. Researchers at OHSU in Portland have revealed a...

A potential way to reduce the risk of postpartum breast cancers

Breast cancers that emerge in young women within a few years after pregnancy are strikingly more dangerous. A new study suggests that the common pain reliever ibuprofen might work as a preventive...

Tumor cells fuse with immune cells and become more aggressive

Egg and sperm cells fuse together to begin a unique new life. Certain muscle and bone cells fuse together during development to gain new properties. But cell fusion also is a process that cancer...

Cancer translated’s top blog posts of 2017

From basic science to survivorship and patient advocacy, the OHSU Knight Cancer Institute’s 'Cancer translated' blog explores new ideas and debates in cancer medicine. We sorted a year’s worth...

Solving the problem of drug-resistant cancer

To discover ways to prevent or delay resistance to cancer therapies, a new NCI-funded center at OHSU is exploring how acute myeloid leukemia cells evolve and adapt. The first successful targeted...

Check out the Knight Cancer pilot project award winners

Preventing skin cancer with a DNA-repair enzyme. Understanding how microRNAs modify cancer immunity. Using zebrafish embryos to rapidly assess toxicity of anticancer drug combinations. These are...

Outsmarting treatment-resistant prostate cancers

Aggressive prostate tumors can rapidly evolve to resist PARP inhibitors, but it may be possible to detect resistance early enough to counteract....