Shannon McWeeney, Ph.D., works at the intersection of computer science, biostatistics, genetics and medicine, finding ways to speed cancer research past the bottlenecks stalling progress. She’s...
Researchers in Oregon have engineered a material that replicates human bone tissue with an unprecedented level of precision, from its microscopic crystal structure to its biological activity. They...
OHSU Knight Cancer Institute scientists have identified key gene networks and signaling pathways that cancerous cells in acute myeloid leukemia use to resist treatment with the drug venetoclax, one...
Cell fusion is one of the ways that tumors can gain abilities to become life-threatening and resist treatment, Melissa Wong, Ph.D., and colleagues first reported last year. The paper now is one of...
Exploring immune therapy combinations to stop aggressive breast cancers. Unraveling the gene changes that make juvenile myelomonocytic leukemia so difficult-to-treat. Developing a biomarker to guide...
Breast cancers that emerge after a woman gives birth are significantly more likely to spread and become life-threatening. And this elevated risk endures for at least 10 years, a new study has...
Cancer-fighting compounds that look promising in the laboratory often fail in human clinical trials. One reason: standard tumor models consist of cancer cells growing in a flat plastic dish with...
One study shows how it may be possible to stop acute myeloid leukemia by targeting a hidden population of cells that support the cancer. Another reveals how AML evolves to evade anti-cancer drugs,...
Even when anti-cancer drugs appear to eliminate tumors, a resistant few malignant cells can survive and allow cancers to resume a fatal onslaught. Researchers at OHSU in Portland have revealed a...
Breast cancers that emerge in young women within a few years after pregnancy are strikingly more dangerous. A new study suggests that the common pain reliever ibuprofen might work as a preventive...
OHSU researchers led by Lisa M. Coussens, Ph.D., have revealed a novel mechanism underlying how cancer cells co-opt complement proteins of the immune system to promote tumor growth. And the...