A clinical trial at OHSU and UC San Francisco points the way to potential targeted therapies. The drug enzalutamide is a mainstay of treatment for men with life-threatening prostate cancer that has...
Cancer is more than just tumor cells driven by gene mutations. Cancer is like an ecosystem filled with evolving populations of tumor cells that interact with and enlist support from neighboring...
A clinical trial at OHSU and UC San Francisco points the way to potential targeted therapies. The drug enzalutamide is a mainstay of treatment for men with life-threatening prostate cancer that has...
Cancer scientists reveal the first direct evidence that leukemia development depends on the order in which mutations occur. Acute myeloid leukemia, or AML, is the most common blood cancer in adults...
Scientists thought they understood the steps leading to acute myeloid leukemia. But one of the basic tenets in that understanding turns out to be unsound, according to researchers at the OHSU Knight...
Researchers in Oregon have engineered a material that replicates human bone tissue with an unprecedented level of precision, from its microscopic crystal structure to its biological activity. They...
OHSU Knight Cancer Institute scientists have identified key gene networks and signaling pathways that cancerous cells in acute myeloid leukemia use to resist treatment with the drug venetoclax, one...
Cell fusion is one of the ways that tumors can gain abilities to become life-threatening and resist treatment, Melissa Wong, Ph.D., and colleagues first reported last year. The paper now is one of...
Exploring immune therapy combinations to stop aggressive breast cancers. Unraveling the gene changes that make juvenile myelomonocytic leukemia so difficult-to-treat. Developing a biomarker to guide...
Breast cancers that emerge after a woman gives birth are significantly more likely to spread and become life-threatening. And this elevated risk endures for at least 10 years, a new study has...
Cancer-fighting compounds that look promising in the laboratory often fail in human clinical trials. One reason: standard tumor models consist of cancer cells growing in a flat plastic dish with...