How scientists are mapping the cancer ecosystem to find cures

Cancer is more than just tumor cells driven by gene mutations. Cancer is like an ecosystem filled with evolving populations of tumor cells that interact with and enlist support from neighboring...

Unraveling early events in a life-threatening leukemia

Cancer scientists reveal the first direct evidence that leukemia development depends on the order in which mutations occur. Acute myeloid leukemia, or AML, is the most common blood cancer in adults...

Study overturns basic tenet in leukemia biology

Scientists thought they understood the steps leading to acute myeloid leukemia. But one of the basic tenets in that understanding turns out to be unsound, according to researchers at the OHSU Knight...

Cancer cell fusion study showcased in Science

Cell fusion is one of the ways that tumors can gain abilities to become life-threatening and resist treatment, Melissa Wong, Ph.D., and colleagues first reported last year. The paper now is one of...

Eleven inspired projects underway with Knight Cancer pilot funds

Exploring immune therapy combinations to stop aggressive breast cancers. Unraveling the gene changes that make juvenile myelomonocytic leukemia so difficult-to-treat. Developing a biomarker to guide...

Long after childbirth, a persistent risk for metastatic breast cancer

Breast cancers that emerge after a woman gives birth are significantly more likely to spread and become life-threatening. And this elevated risk endures for at least 10 years, a new study has...