What magnitude of benefit is meaningful to cancer patients?

Oncologists often use the phrase "clinically meaningful benefit" to describe the effect of an experimental treatment. But is the benefit meaningful for patients? A new paper suggests that benefit...

Clearing the quandary of cancer early detection

For many cancers, five-year survival rates approach 99 percent if the disease is detected early, when tumors are small and not yet spreading. But efforts to detect cancers early have led to a...

When evidence contradicts entrenched medical practices

Medical reversal is the phenomenon when a medical practice falls out of favor not by being surpassed, but when researchers discover that it didn't really work all along. “I think the lesson of...

Charting the financial conflicts of doctors on Twitter

A detailed look at the tweeting habits of more than 600 hematologist-oncologists found that 72 percent were recipients of industry money for consulting, travel, lodging, or food and beverage. It's...

News hype clouds public understanding of cancer research

Breakthrough. Game changer. Revolutionary. Transformative. Life saver. A new analysis of media coverage found that half of new cancer drugs described with such superlatives had not received Food and...