Sex hormones limit cancer immunotherapy success
Scientists have discovered how the sex hormone androgen, most commonly testosterone in men, can limit the body’s response to cancer immunotherapy, a finding that may help make those therapies more...
Time to accelerate early detection research
Cancer early detection research is poised to transform patient survival, but significant hurdles stand in the way of translating new findings into clinical application, leaders of the field assert in...
Study reveals inherited risk of leukemia
Inherited mutations that increase the risk of developing a dangerous blood cancer are more common than previously appreciated, a new study reveals. Researchers analyzed acute myeloid leukemia...
Detecting tumor responses before they become deadly
Targeted cancer therapies can be stunningly effective at blocking specific, cancer-driving signals. But all too often, tumors develop resistance by switching to alternative signaling pathways to...
How to help cancer patients with bone metastases get the benefits of exercise
An international panel including OHSU's Kerri Winters-Stone, Ph.D., has published best practice recommendations on exercise for people with cancer that has spread to their bones. "This consensus...
Knight Cancer signal achievements of 2021
In a year that was anything but normal, the OHSU Knight Cancer Institute’s people stepped up and continued to do great things. From basic research, to patient care, to impact in the community, the...
New clues to what turns prostate cancers deadly
Only a fraction of prostate cancers become life threatening, but it’s impossible to predict which ones. In a surprising new study, researchers found that two signaling proteins used by nerve cells...
Seven at OHSU among world’s most influential scientists
Seven OHSU scientists are among the world's most highly cited, according to the consulting and data analysis firm Clarivate, which compiles an annual list of researchers who have demonstrated...
Jamming fat metabolism stops blood cancer cells
Targeted cancer therapies work by blocking specific, cancer-driving mutations. But in a new laboratory study, researchers show that cancers driven by several different mutations can all be stopped by...
‘Scissor’ opens view to single cells of cancer, other diseases
Cancerous tumors are composed of cells that may look the same but are in fact incredibly diverse. Mutations and changes in gene activity give rise to competing sub-populations of tumor cells with...