Study reveals inherited risk of leukemia

Inherited mutations that increase the risk of developing a dangerous blood cancer are more common than previously appreciated, a new study reveals. Researchers analyzed acute myeloid leukemia...

Detecting tumor responses before they become deadly

Targeted cancer therapies can be stunningly effective at blocking specific, cancer-driving signals. But all too often, tumors develop resistance by switching to alternative signaling pathways to...

Knight Cancer signal achievements of 2021

In a year that was anything but normal, the OHSU Knight Cancer Institute’s people stepped up and continued to do great things. From basic research, to patient care, to impact in the community, the...

New clues to what turns prostate cancers deadly

Only a fraction of prostate cancers become life threatening, but it’s impossible to predict which ones. In a surprising new study, researchers found that two signaling proteins used by nerve cells...

Seven at OHSU among world’s most influential scientists

Seven OHSU scientists are among the world's most highly cited, according to the consulting and data analysis firm Clarivate, which compiles an annual list of researchers who have demonstrated...

Jamming fat metabolism stops blood cancer cells

Targeted cancer therapies work by blocking specific, cancer-driving mutations. But in a new laboratory study, researchers show that cancers driven by several different mutations can all be stopped by...

‘Scissor’ opens view to single cells of cancer, other diseases

Cancerous tumors are composed of cells that may look the same but are in fact incredibly diverse. Mutations and changes in gene activity give rise to competing sub-populations of tumor cells with...

Targeting uniquely dangerous postpartum breast cancers

Breast cancers that emerge within five to ten years of pregnancy are more likely to become life-threatening. A new study finds that these postpartum breast tumors represent a unique subtype of cancer...