Overcoming drug resistance to stop a deadly blood cancer

Cancer researchers have discovered a potential way to make targeted therapy drugs more effective and longer lasting for people with acute myeloid leukemia, or AML. The scientists showed how it is...

First-in-class drug targets resistant ovarian cancer

Cancer researchers have discovered a way to target a pivotal driver of drug resistance in ovarian cancer, one of the top causes of cancer death in women. The experimental compound, called SU056,...

Perturbed tumors reveal their secrets

A trove of freely accessible cancer data helps researchers find new combination treatments. Targeted cancer therapies work by blocking a specific cancer-driving signal, thus limiting harm to healthy...

Stopping the secretive cells that revive deadly tumors

Cancers are notorious for their ability to rebound uncontrollably after a first round of successful treatment. In a new study, researchers at OHSU have uncovered how a fraction of a tumor’s cells...

New path to stop drug-resistant breast cancer

Even when anti-cancer drugs appear to eliminate tumors, a resistant few malignant cells can survive and allow cancers to resume a fatal onslaught. Researchers at OHSU in Portland have revealed a...

Solving the problem of drug-resistant cancer

To discover ways to prevent or delay resistance to cancer therapies, a new NCI-funded center at OHSU is exploring how acute myeloid leukemia cells evolve and adapt. The first successful targeted...