Sex hormones limit cancer immunotherapy success

Scientists have discovered how the sex hormone androgen, most commonly testosterone in men, can limit the body’s response to cancer immunotherapy, a finding that may help make those therapies more...

How to make more cancers vulnerable to immunotherapies

Cancer immunotherapies called checkpoint inhibitors can bring dramatic, life-saving results – but only for a limited fraction of patients. Aiming to help more patients benefit, researchers in...

Advancing immunotherapy for life-threatening prostate cancer

Restoring tumor-specific immunity is a treatment strategy that has worked well, but only against some cancers. Research led by OHSU oncologist Julie Graff, M.D., revived hope that the approach may...

A potential way to reduce the risk of postpartum breast cancers

Breast cancers that emerge in young women within a few years after pregnancy are strikingly more dangerous. A new study suggests that the common pain reliever ibuprofen might work as a preventive...

A new way to guide cancer immune therapy

Scrutinizing the immune cells infiltrating a tumor may reveal the cancer's vulnerability or resistance to immune-based therapies. Cancer immune therapies have delivered life-saving, long-lasting...

For rare tumors, a far-reaching trial of immunotherapy

The first federally funded clinical trial of immunotherapy for rare cancers launched this week under the auspices of SWOG, the research consortium headquartered at the OHSU Knight Cancer...