Unlocking the combination to target evasive kidney cancers
Roughly one in four people with kidney cancer have a type that does not respond to targeted therapy drugs, leaving no proven treatment options for those whose tumors have started to...
Tag: targeted therapy
Perturbed tumors reveal their secrets
A trove of freely accessible cancer data helps researchers find new combination treatments. Targeted cancer therapies work by blocking a specific cancer-driving signal, thus limiting harm to healthy...
For veterans with prostate cancer, a new center of excellence in Oregon
VA Portland Health Care System and OHSU are launching a precision oncology center of excellence supported by the Prostate Cancer Foundation. On Veteran's Day, the foundation announced $5 million in...
Beat AML study paves way for precision treatment
Using genetic information to match patients to targeted therapies may improve survival in people with a fast-moving leukemia. Because acute myeloid leukemia is such a fast-moving and deadly cancer,...
Dive into the science of precision cancer medicine at Knight School
Targeted therapy drugs have transformed the outlook for people diagnosed with one form of blood cancer, chronic myeloid leukemia. A disease with a three- to five-year life expectancy became, for...
How a deadly leukemia develops resistance to one of the newest targeted therapies
OHSU Knight Cancer Institute scientists have identified key gene networks and signaling pathways that cancerous cells in acute myeloid leukemia use to resist treatment with the drug venetoclax, one...
Targeting osteosarcoma, a cancer more common in young people
Knight Cancer researchers describe positive results with the drug regorafenib. Osteosarcoma is a bone cancer that disproportionately affects teenagers, and despite substantial efforts, outcomes for...
Studies reveal new ways to fight a deadly leukemia
One study shows how it may be possible to stop acute myeloid leukemia by targeting a hidden population of cells that support the cancer. Another reveals how AML evolves to evade anti-cancer drugs,...
New path to stop drug-resistant breast cancer
Even when anti-cancer drugs appear to eliminate tumors, a resistant few malignant cells can survive and allow cancers to resume a fatal onslaught. Researchers at OHSU in Portland have revealed a...
Positive results with a targeted therapy for osteosarcoma, a cancer more common in young people
Osteosarcoma is a bone cancer that disproportionately affects teenagers, and outcomes for patients have changed little in decades. Now researchers, including two OHSU Knight Cancer Institute...