OHSU Doernbecher researchers receive Gates Foundation grant to advance tuberculosis vaccine research

David Lewinsohn, M.D., Ph.D., in the Papé Family Pediatric Research Institute at OHSU Doernbecher Children’s Hospital, has been awarded a $3 million grant from the Bill & Melinda Gates Foundation to study whether a particular group of infection-fighting cells, known as T cells, may be viable for the development of a vaccine aimed at combatting the global tuberculosis epidemic.

According to the World Health Organization’s 2015 global report, TB claimed 1.5 million lives in 2014 — 140,000 of which were children — making it the leading cause of death worldwide. TB is a contagious airborne disease caused by the bacteria Mycobacterium tuberculosis. It generally attacks the lungs, though may spread to various parts of the body such as the kidney, spine and brain.

This three-year research project brings together collaborators from OHSU, the University of Chicago, the University of Oklahoma Health Sciences University, Colorado State University, La Jolla Institute of Allergy and Immunology, and Stanford University. Read the full media release.