Eric Gouaux’s serotonin transporter research featured by NIH

CaptureRecent findings by Vollum Institute senior scientist, Eric Gouaux, Ph.D., and team that reveal the molecular structure of the human serotonin transporter, are getting a lot of attention from the biomedical community and the media. Gouaux’s study was featured in NIH Research Matters, the online publication that highlights groundbreaking NIH-funded discoveries. The article, “Serotonin transporter structure revealed,” discusses the innovative technique developed by the team that allowed them to use X-ray crystallography to capture a 3-D image of the protein. “The technique yielded a detailed molecular map of the human serotonin transporter’s structure… The researchers could also see where genetic variations associated with various psychiatric disorders are located in the transporter. Knowing the structure of the transporter can help researchers gain insights into the molecular causes of these disorders and of antidepressant treatment resistance.”