Studies in genomics, transcriptomics and epigenomics have shaped the understanding of cellular complexity and heterogeneity. Technological advances are now enabling cost-efficient, high-throughput analysis of biological molecules and have offered researchers an opportunity to combine the interrogation of DNA, RNA and epigenome in order to better understand genotype-phenotype interactions.
Learn more about OHSU core services and the Epigenetics Consortium from Christina Harrington and Lucia Carbone. The seminar will include a review of recent research that incorporates multi-omic approaches and introduces the tools that enable this research, including sequencing and array-based technologies. Thursday, March 14
10 a.m. to noon
Richard Jones Hall, room 4320
Space is limited, register now for this free event.
Leveraging sequencing and arrays for understanding biological complexity
Jonathan Bibliowicz, Ph.D., senior sequencing specialist, Illumina, Inc.
Resources and support available from OHSU Integrated Genomics Lab Cores
Christina Harrington, Ph.D., director, Integrated Genomics Lab and Gene Profiling Shared Resource
The cores of the Integrated Genomics Lab can provide support with nucleic acid extraction, real-time PCR, microarrays and high-throughput short-read sequencing. The Gene Profiling Shared Resource is able to provide support with DNA extraction for genotyping and methylation profiling studies and offers services for assays utilizing DNA arrays for whole-genome genotyping and methylation profiling.
The Knight Cardiovascular Institute Epigenetics Consortium: Enabling epigenetics research at OHSU
Lucia Carbone, Ph.D., director, Epigenetics Consortium, Knight Cardiovascular Institute
If you are studying gene regulation, you are studying epigenetics. The Epigenetics Consortium assists investigators to analyze epigenetic regulation taking advantage of constantly evolving technologies and high-throughput sequencing. The consortium supports projects from start to finish, including study design, assays, bioinformatic analyses and interpretation of the results. Hear an overview of the services offered to OHSU investigators, including data analysis and possible applications.
Coffee and snacks will be provided.